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Tuesday, 8 October 2013

Nanotechnology and drug delivery systems – model question paper for B.Tech/M.Tech Nanotechnology



1(a) What is active targeting and passive targeting in drug delivery? (8 Marks)
(b) What is ADME hypothesis? (6 Marks)
(c) Write a note on metabolism based drug targeting. (6 Marks)
2(a) Explain the structure of Liposome and outline any one method for its preparation. (8 Marks)
(b) Distinguish between cubosomes and hexosomes. (4 Marks)
(c) Explain physiochemical principles of nanosized drug delivery systems. (4 Marks)
(d) Explain how nanoparticles are used for crossing biological membranes. (4 Marks)
3(a) Explain any two surface charcterisation tools. (6 Marks)
(b) Write notes on bioconjugation and pegylation. (6 Marks)
(c) Explain how gold nanoparticles are used in drug delivery. (4 Marks)
(d) Write a note on virus based nanoparticles. (4 Marks)
4(a) How will you classify liposomal nanoparticles based on number of layers? (4 Marks)
(b) Write a note on applications of liposomes in cosmetic industry. (4 Marks)
(c) What are lipid-DNA complexes? (4 Marks)
(d) Write a note on lipid based drug delivery syatems for peptide and protein drug delivery. (8 Marks)
5(a) What is EPR effect? What is its role in drug delivery? (8 Marks)
(b) What are folate receptors? (4 Marks)
(c) Distinguish between paclitaxel and doxorubicin. (8 Marks)
6(a) What are dendrimers. Mention some examples. (6 Marks)
(b) What are nanoscale containers? (4 Marks)
(c) Write a note on biocompatibility of polymer micelles as drug carriers. (6 Marks)
(d) Mention some magnetic particles which can be used as drug carriers. (4 Marks)
7(a) What is drug detection? Explain how resonance light scattering is useful for drug detection. (8 Marks)
(b) Mention the benefits of nano imaging agents. (4 Marks)
(c) Write a note on nanobiosensors. (4 Marks)
(d) Write a note on nanorobots. (4 Marks)
8(a) Write and explain protocols for nanodrug administration. (6 Marks)
(b) Mention some Nanomaterials used in diagnostic and therapeutic applications. (4 Marks)
(c) What are molecular nanomachines? (4 Marks)
(d) What is nanotribology? Mention its applications. (6 Marks)

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